Hepatoid tumor

Hepatoid tumor or hepatoid [adeno]carcinoma are terms for a number of uncommon or rare neoplasms in humans, named for a visual resemblance of the cells under the microscope to those of hepatocellular carcinoma, the most common form of liver cancer. They can arise in several parts of the body, and thus form sub-types of diseases such as stomach cancer and pancreatic cancer.^[1]^[2]^[3] The WHO defines "Hepatoid carcinoma" as "An adenocarcinoma with morphologic characteristics similar to hepatocellular carcinoma, arising from an anatomic site other than the liver".^[4]

In dogs it may refer to a Perianal gland tumor, based on a similar resemblance to healthy liver cells.

References

^ Gálvez-Muñoz, Elisa; Gallego-Plazas, Javier; Gonzalez-Orozco, Verónica; Menarguez-Pina, Francisco; Ruiz-Maciá, José A; Morcillo, Miguel A (2009). "Hepatoid adenocarcinoma of the stomach – a different histology for not so different gastric adenocarcinoma: a case report". International Seminars in Surgical Oncology. 6 (1): 13. doi:10.1186/1477-7800-6-13. PMC 2731104. PMID 19674468.
^ Soofi, Yousef; Kanehira, Kazunori; Abbas, Ali; Aranez, Jose; Bain, Andrew; Ylagan, Lourdes (August 2014). "Pancreatic hepatoid carcinoma: A rare form of pancreatic neoplasm". Diagnostic Cytopathology. 43 (3): 251–256. doi:10.1002/dc.23195. PMID 24965084.
^ Vlachostergios, Panagiotis J; Voutsadakis, Ioannis A; Barbanis, Sotirios; Karasavvidou, Foteini; Papandreou, Christos N (2009). "AFP-producing hepatoid adenocarcinoma of the stomach: a case report". Cases Journal. 2 (1): 9296. doi:10.1186/1757-1626-2-9296. PMC 2803960. PMID 20062620.
^ "WHO Classification of Tumours, Hepatoid carcinoma". IARC. World Health Organization. Archived from the original on 12 February 2015. Retrieved 2 December 2014.

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[1] Gálvez-Muñoz, Elisa; Gallego-Plazas, Javier; Gonzalez-Orozco, Verónica; Menarguez-Pina, Francisco; Ruiz-Maciá, José A; Morcillo, Miguel A (2009). "Hepatoid adenocarcinoma of the stomach – a different histology for not so different gastric adenocarcinoma: a case report". International Seminars in Surgical Oncology. 6 (1): 13. doi:10.1186/1477-7800-6-13. PMC 2731104. PMID 19674468.

[2] Soofi, Yousef; Kanehira, Kazunori; Abbas, Ali; Aranez, Jose; Bain, Andrew; Ylagan, Lourdes (August 2014). "Pancreatic hepatoid carcinoma: A rare form of pancreatic neoplasm". Diagnostic Cytopathology. 43 (3): 251–256. doi:10.1002/dc.23195. PMID 24965084.

[3] Vlachostergios, Panagiotis J; Voutsadakis, Ioannis A; Barbanis, Sotirios; Karasavvidou, Foteini; Papandreou, Christos N (2009). "AFP-producing hepatoid adenocarcinoma of the stomach: a case report". Cases Journal. 2 (1): 9296. doi:10.1186/1757-1626-2-9296. PMC 2803960. PMID 20062620.

[4] "WHO Classification of Tumours, Hepatoid carcinoma". IARC. World Health Organization. Archived from the original on 12 February 2015. Retrieved 2 December 2014.

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