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Richard Scheller

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Richard H. Scheller
Scheller in 1980
Born (1953-10-30) October 30, 1953 (age 71)
Milwaukee, Wisconsin, US
Alma materUniversity of Wisconsin–Madison, California Institute of Technology, Columbia University
Known forHead of gRED
AwardsNAS Award in Molecular Biology (1997)
Kavli Prize (2010)
Albert Lasker Award for Basic Medical Research (2013)
Scientific career
FieldsNeuroscience
InstitutionsGenentech, University of California San Francisco
Doctoral advisorEric H. Davidson
Other academic advisorsEric Kandel, Richard Axel

Richard H. Scheller (born 30 October 1953) is the former chief science officer and head of therapeutics at 23andMe and the former executive vice president of research and early development at Genentech.[1] He was a professor at Stanford University from 1982 to 2001 before joining Genentech. He has been awarded the Alan T. Waterman Award in 1989, the W. Alden Spencer Award in 1993 and the NAS Award in Molecular Biology in 1997, won the 2010 Kavli Prize in Neuroscience with Thomas C. Südhof and James E. Rothman, and won the 2013 Albert Lasker Award for Basic Medical Research with Thomas Südhof. He was also given the Life Sciences Distinguished Alumni Award from University of Wisconsin–Madison. He is a Fellow of the American Academy of Arts and Sciences and a Member of the National Academy of Sciences.

Biography

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He earned his B.S. in biochemistry from the University of Wisconsin–Madison and his Ph.D. in chemistry from the California Institute of Technology under the guidance of Eric H. Davidson.[2] While a graduate student, he worked with Keiichi Itakura and Arthur Riggs to help synthesize Somatostatin for Herb Boyer at Genentech.[3] After finishing his graduate studies, he did a brief postdoc with Davidson and later with Eric Kandel and Richard Axel at Columbia University.[1] While at Columbia, he extended his previous work with recombinant DNA to identify the egg-laying hormone (ELH) gene family of neuropeptides.[4]

Scheller joined the Stanford University faculty in the Department of Biological Sciences in 1982 and later the Department of Molecular and Cellular Physiology. He was an investigator with the Howard Hughes Medical Institute from 1990 to 2001.[5] While at Stanford, he cloned and identified the proteins that control neurotransmitter release notably those in the Syntaxin family of transport proteins, Rab GTPases, and SNAREs.[6]

In 2001, he was recruited from Stanford to join Genentech as a senior vice president and chief research officer, replacing Dennis Henner.[7] In 2008, was named the chief scientific officer and executive vice president of research. After the acquisition of Genentech by Hoffmann-La Roche, he was appointed the head of Genentech research and early development and a member of the enlarged Roche Corporate Executive Committee.[8] He is concurrently an adjunct professor in the Department of Biochemistry and Biophysics at the University of California San Francisco.

In March 2015, Scheller joined 23andMe as the chief scientific officer and head of therapeutics, creating and leading their therapeutics team, which translates genetic data into discovery and development of new drug therapies.[9]

Scheller is also known as an expert and enthusiastic collector of traditional and historical African art, since the 1980s. An article about his passion for African art appeared in Tribal Arts Magazine,[10] and some of his extensive collection was exhibited and published with the 2015 show entitled "Embodiments" at the De Young Museum in San Francisco.

Awards

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Personal life

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He is married to Susan McConnell, a professor in the Department of Biology at Stanford University, and lives on Stanford Campus.

References

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  1. ^ a b "Richard Scheller (KavliPrize.no)". Archived from the original on 22 February 2013. Retrieved 24 August 2012.
  2. ^ "Studies of cloned repetitive DNA sequences in the sea urchin genome"
  3. ^ "Richard Scheller/Autobiography". Retrieved 24 August 2012.
  4. ^ "Richard Axel - Autobiography". Nobelprize.org. Retrieved 24 August 2012.
  5. ^ "Richard H. Scheller, Ph.D." Howard Hughes Medical Institute. Retrieved 24 August 2012.
  6. ^ Bennett, M.; Calakos, N; Scheller, R. (10 July 1992). "Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones". Science. 257 (5067): 255–259. Bibcode:1992Sci...257..255B. doi:10.1126/science.1321498. PMID 1321498.
  7. ^ Abate, Tom (22 January 2001). "Genentech Raids Stanford Lab". SF Chronicle. Retrieved 24 August 2012.
  8. ^ "Roche and Genentech announce organizational and leadership decisions". 14 April 2009. Archived from the original on 19 April 2009. Retrieved 24 August 2012.
  9. ^ Leuty, Ron (2015-03-12). "23andMe grabs former Genentech science boss, will develop drugs". www.bizjournals.com. Retrieved 2017-05-09.
  10. ^ "Tribal Art Magazine - Issue #74 - Winter 2014 XIX-1 (sample pages)". www.tribalartmagazine.com. Retrieved 2017-05-09.
  11. ^ "Distinguished Alumni Awards". Caltech Alumni Association. Retrieved 2017-05-09.
  12. ^ "Richard Scheller". www.nasonline.org. Retrieved 2020-07-03.
  13. ^ "Gruppe 6: Cellebiologi og molekylærbiologi" (in Norwegian). Norwegian Academy of Science and Letters. Retrieved 30 March 2016.
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