Trimethoprim/polymyxin B
| Combination of | |
|---|---|
| Polymyxin B | Cell envelope antibiotic |
| Trimethoprim | Nucleic acid inhibitor antibiotic |
| Clinical data | |
| Trade names | Polytrim |
| Routes of administration | Topical eye drops |
| ATC code | |
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Polymyxin B/trimethoprim, sold under the brand name Polytrim is an antimicrobial solution for topical ophthalmic use in the treatment of acute bacterial conjunctivitis and blepharoconjunctivitis.[1]
In 2022, it was the 252nd most commonly prescribed medication in the United States, with more than 1 million prescriptions.[2][3]
Medical uses
[edit]Polymyxin B/trimethoprim is indicated in the treatment of surface ocular bacterial infections,[4] including acute bacterial conjunctivitis, and blepharoconjunctivitis, caused by susceptible strains of the following microorganisms: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus viridans, Haemophilus influenzae, and Pseudomonas aeruginosa.[1]
References
[edit]- ^ a b c "Polytrim (polymyxin B sulfate and trimethoprim ophthalmic solution, USP) Sterile". DailyMed. Retrieved 6 December 2024.
- ^ "The Top 300 of 2022". ClinCalc. Archived from the original on 30 August 2024. Retrieved 30 August 2024.
- ^ "Polymyxin B; Trimethoprim Drug Usage Statistics, United States, 2013 - 2022". ClinCalc. Retrieved 30 August 2024.
- ^ Yolton DP (1992). "New antibacterial drugs for topical ophthalmic use". Optometry Clinics. 2 (4): 59–72. PMID 1286241.
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