AKR7A3

AKR7A3
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2CLP
Identifiers
Aliases	AKR7A3, AFAR2, aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase), aldo-keto reductase family 7 member A3
External IDs	OMIM: 608477; HomoloGene: 49295; GeneCards: AKR7A3; OMA:AKR7A3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	19,288,770 bp
RNA expression pattern
	Top expressed in
	duodenum; ; jejunal mucosa; ; body of pancreas; ; mucosa of transverse colon; ; right lobe of liver; ; mucosa of ileum; ; pancreatic ductal cell; ; human kidney; ; cardia; ; body of stomach;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	electron transfer activity; oxidoreductase activity; aldo-keto reductase (NADP) activity; protein binding; identical protein binding; alditol:NADP+ 1-oxidoreductase activity;
Cellular component	cytoplasm; extracellular exosome; cytosol;
Biological process	xenobiotic metabolic process; cellular aldehyde metabolic process; electron transport chain; aflatoxin metabolic process; aflatoxin catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	22977
	n/a
	ENSG00000162482
	n/a
	O95154
	n/a
	NM_012067
	n/a
	NP_036199
	n/a
	Wikidata
View/Edit Human

Aldo-keto reductase family 7 member A3 is a protein that in humans is encoded by the AKR7A3 gene. ^[3]

Function

Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004].

PDBe-KB provides an overview of all the structure information available in the PDB for Human Aflatoxin B1 aldehyde reductase member 3 (AKR7A3)