Calcium channel associated transcriptional regulator

Calcium channel associated transcriptional regulator (CCAT) is a transcription factor found in mammalian cells.

Generation

In neuronal cells, CCAT is generated upon activation of a cryptic promoter in exon 46 of CACNA1C, the gene that encodes the voltage-gated calcium channel Cav1.2.^[1]

References

^ Gomez-Ospina, Natalia; Panagiotakos, Georgia; Portmann, Thomas; Pasca, Sergiu P.; Rabah, Dania; Budzillo, Agata; Kinet, Jean Pierre; Dolmetsch, Ricardo E. (16 April 2013). "A Promoter in the Coding Region of the Calcium Channel Gene CACNA1C Generates the Transcription Factor CCAT". PLOS ONE. 8 (4): e60526. Bibcode:2013PLoSO...860526G. doi:10.1371/journal.pone.0060526. ISSN 1932-6203. PMC 3628902. PMID 23613729.

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[1] Gomez-Ospina, Natalia; Panagiotakos, Georgia; Portmann, Thomas; Pasca, Sergiu P.; Rabah, Dania; Budzillo, Agata; Kinet, Jean Pierre; Dolmetsch, Ricardo E. (16 April 2013). "A Promoter in the Coding Region of the Calcium Channel Gene CACNA1C Generates the Transcription Factor CCAT". PLOS ONE. 8 (4): e60526. Bibcode:2013PLoSO...860526G. doi:10.1371/journal.pone.0060526. ISSN 1932-6203. PMC 3628902. PMID 23613729.

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