Carbazole alkaloids
The carbazole alkaloids are natural products of the indole alkaloid type, derived from carbazole.[1]
Occurrence
[edit]Carbazole alkaloids with unsubstituted benzene rings occur rarely. Olivacin has been found in the bark of Aspidosperma olivaceum and ellipticin in Ochrosia elliptica.[2] Some carbazole alkaloids, especially glybomin B, have been isolated from Glycosmis pentaphylla.[3]
Representatives
[edit]Representatives include, among others, glycozoline, olivacine and ellipticin[2] and further glybomine B.[3]
-
Glycozoline -
Olivacine -
Ellipticin -
Glybomine B
Properties
[edit]Carbazole alkaloids have cytotoxic and antifungal properties. Furthermore, they have detrimental effects against HIV viruses and tumor cells.[3] Olivacin has fluorescent properties.[2]
References
[edit]- ^ Entry on carbazole alkaloids. In: Römpp Online. Georg Thieme Verlag, accessed May 31, 2020.
- ^ a b c Eberhard Breitmaier (1997), Alkaloide, Wiesbaden: Springer Fachmedien, p. 49, ISBN 978-3-519-03542-8
- ^ a b c G. Yang, Y. Wu, Y. Chen (2012), "Alkaloids from the Stems of Glycosmis pentaphylla", Helvetica Chimica Acta, vol. 95, no. 8, pp. 1449–1454, doi:10.1002/hlca.201200027
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External links
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