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Claudio Tiribelli

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Claudio Tiribelli
MD, PhD
Claudio Tiribelli
Born (1946-10-06) October 6, 1946 (age 78)
Venice (Italy)
NationalityItalian
Education
Occupation(s)Scientific Director, Italian Liver Foundation, NPO
Organization(s)EASL, AASLD, APASL, IASL, Global Liver Foundation
Honours
Medical career
ProfessionClinical medical practice, teaching and research
Fieldgastroenterology, hepatology, obesity
InstitutionsUniversity of Trieste Units
Sub-specialtiesBilirubin neurotoxicity
Researchbilirubin, neonatal jaundice, metabolic liver diseases, HCC, stem cells in HCC
Websitehttps://www.fegato.it/eng/claudio-tiribelli/

Claudio Tiribelli (born 6 October 1946) is an Italian hepatologist best known for his studies on bilirubin and Kernicterus, a bilirubin-induced neurological condition.[1]

Biography

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Born in Venice in 1946, Claudio Tiribelli graduated in Medicine and Surgery at the University of Padua and specialized in Gastroenterology at the University of Trieste.

After many experiences abroad, at the University of Groningen (Netherlands), the University of Toronto (Canada) and the Polytechnic University of Brooklyn (USA), Claudio Tiribelli returned to Italy at the University of Trieste, where since 1989 to 2008 he was Full Professor of Clinical Biochemistry and from 2009 to 2016 was Full Professor of Gastroenterology.

Previously Director of the Liver Pathologies Clinic and of the Department of Medicine at the Cattinara Hospital (Trieste), he was creator and Scientific Director of the Italian Liver Foundation - NPO, based at AREA Science Park in Basovizza. In Argentina he collaborated in the creation of the CAIC – Italian  Argentinian Center for Cryobiology, the study of cryopreservation of cells and organs for medical purposes and for transplants.

For his merits and scientific contributions in international relations, in 2011 Prof. Tiribelli received the Honoris Causa Degree from the Universidad Favaloro in Argentina and in 2012 the Honoris Causa Degree, from the Universidad Nacional de Rosario in Argentina. In 2017 was awarded of the prestigious Leloir Prize, conferred to foreign experts who contributed to the enrichment of international cooperation with Argentina.

Scientific activity

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Since very early in his career, Tiribelli was fascinated by bilirubin.[2] Expanding upon his research activity and expertise, he founded Bilimetrix together with Richard Wennberg. Bilimetrix developed the first point-of-care device for measuring bilirubin in newborns. Early detection of harmful bilirubin levels would prevent neonatal jaundice and allow the newborns to receive timely and proper treatment.

Due to his clinical activity and research interests, he is active in translational activity in several liver disorders as fatty liver disease and hepatocellular carcinoma. Together with his longstanding research associate Stefano Bellentani, he designed and performed the Dionysus Study,[3][4] the first project exploring the prevalence and incidence of liver diseases in the general population.

Expert hepatologist, he is known above all for his studies on bilirubin and in particular on Kernicterus, a neurological damage induced by bilirubin. He is the creator and still Scientific Director of the Italian Liver Foundation - NPO,[5] based at AREA Science Park in Basovizza, a research institution with focus on liver disease and its related pathologies.

He has more than 350 publications in peer-reviewed journals, as well as reviews, editorials, and book chapters. H-index 82 (46 since 2019)[6]

Scientific publications

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Claudio has over 350 scientific publications,[7] some of his most cited works are:

  • "Bilirubin-Induced Neurologic Damage — Mechanisms and Management Approaches"[1]
  • "Prevalence of chronic liver diseases in the general population of Northern Italy: The Dionysos study"[4]
  • "Prevalence And Risk Factors For Hepatic Steatosis In Northern Italy"[3]
  • "The fatty liver index: a simple and accurate predictor of hepatic steatosis in the general population"[8]
  • "Molecular basis and mechanisms of progression of nonalcoholic steatohepatitis (NASH)"[9]
  • "Intestinal Integrity, the Microbiome and Inflammation"[10]

References

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  1. ^ a b Watchko, Jon F.; Tiribelli, Claudio (21 November 2013). Ingelfinger, Julie R. (ed.). "Bilirubin-Induced Neurologic Damage — Mechanisms and Management Approaches". New England Journal of Medicine. 369 (21): 2021–2030. doi:10.1056/NEJMra1308124. ISSN 0028-4793. PMID 24256380.
  2. ^ "claudio tiribelli bilirubin - Search Results - PubMed". PubMed. Retrieved 11 August 2021.
  3. ^ a b Bellentani, Stefano; Saccoccio, Gioconda; Masutti, Flora; Crocè, Lory S.; Brandi, Giovanni; Sasso, Franco; Cristanini, Giovanni; Tiribelli, Claudio (18 January 2000). "Prevalence of and Risk Factors for Hepatic Steatosis in Northern Italy". Annals of Internal Medicine. 132 (2): 112–117. doi:10.7326/0003-4819-132-2-200001180-00004. ISSN 0003-4819. PMID 10644271. S2CID 25141053.
  4. ^ a b Bellentani, Stefano; Tiribelli, Claudio; Saccoccio, Gioconda; Sodde, Marino; Fratti, Nicoletta; De Martin, Christina; Christianini, Giovanni (1 December 1994). "Prevalence of chronic liver disease in the general population of northern Italy: The dionysos study". Hepatology. 20 (6): 1442–1449. doi:10.1002/hep.1840200611. PMID 7982643. S2CID 9045590.
  5. ^ "Fondazione Italiana Fegato". FONDAZIONE ITALIANA FEGATO. Retrieved 26 April 2024.
  6. ^ "Claudio Tiribelli". scholar.google.com. Retrieved 26 April 2024.
  7. ^ "tiribelli c - Search Results - PubMed". PubMed. Archived from the original on 1 May 2021. Retrieved 29 July 2021.
  8. ^ Bedogni, Giorgio; Bellentani, Stefano; Miglioli, Lucia; Masutti, Flora; Passalacqua, Marilena; Castiglione, Anna; Tiribelli, Claudio (2 November 2006). "The Fatty Liver Index: a simple and accurate predictor of hepatic steatosis in the general population". BMC Gastroenterology. 6 (1): 33. doi:10.1186/1471-230X-6-33. ISSN 1471-230X. PMC 1636651. PMID 17081293.
  9. ^ Marra, Fabio; Gastaldelli, Amalia; Svegliati Baroni, Gianluca; Tell, Gianluca; Tiribelli, Claudio (22 January 2008). "Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis". Trends in Molecular Medicine. 14 (2): 72–81. doi:10.1016/j.molmed.2007.12.003. PMID 18218340.
  10. ^ Vítek, Libor; Tiribelli, Claudio (13 August 2020). Phimister, Elizabeth G. (ed.). "Bilirubin, Intestinal Integrity, the Microbiome, and Inflammation". New England Journal of Medicine. 383 (7): 684–686. doi:10.1056/NEJMcibr2013250. ISSN 0028-4793. PMID 32786195. S2CID 221126495.

 

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