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Draft:Karin Roelofs

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Karin Roelofs
Karin_Roelofs_in_2016_bij_Universiteit_van_Nederland
Born
Karin Roelofs

1972
NationalityDutch
Alma materRadboud University
Scientific career
Fields
  • Neuroscience
  • Psychopathology
  • Affective Neuroscience
  • Emotion regulation
  • Defensive threat responses
  • Decisions under threat
Institutions
ThesisDisturbed information processing in conversation disorder. An empirical evaluation of dissociation theory (2002)
Doctoral advisorProf. dr. C.A.L. Hoogduin & Prof. dr. G.P. Van Galen
Websitehttps://www.epanlab.nl/people/karin-roelofs/

Karin Roelofs (1972)[citation needed] is a cognitive neuroscientist and clinical psychologist known for her contributions in the fields of stress resilience[1], defensive freeze reactions in humans[2], neurocognitive mechanisms of emotion regulation in health[3], professionals at risk[4] and patients with stress-related disorders[5]. Currently she holds the position of Professor of Experimental Psychopathology at the Behavioural Science Institute (BSI) and is chair of the Affective Neuroscience group at the Donders Institute for Brain Cognition and Behaviour (DI), Radboud University Nijmegen (RU) in The Netherlands. Roelofs is a member of the Dutch Royal Academy for Sciences[6].

Education and Career[edit]

Karin Roelofs obtained her Master's Degree in Neuropsychology and Clinical Psychology at Radboud University. Afterward, Roelofs took on a research fellowship, assuming the position of junior researcher at the Pediatric Branch NCI: National Institutes of Health (NIH) in Bethesda, USA. She completed her Ph.D. in 2002 at Radboud University, with the highest distinction (Cum Laude) and became assistant professor at the Department of Clinical Health and Neuropsychology at Leiden University (LU). During this time, she also held part-time positions as a registered GZ-Psycologist[7] at Rivierduinen, Leiden and at PsyQ, Den Haag. In 2007 she was promoted to Associate professor specifically at the Leiden Institute for Brain and Cognition (LIBC). Following her tenure at Leiden University, she made a transition in 2010 to Radboud University as a full professor of Experimental Psychopathology at Behavioural Science Institute (BSI) & Donders Institute: Centre for Cognitive Neuroimaging (DCCN). It was there that she founded the EPAN group[8], known as "Experimental Psychopathology and Affective Neuroscience”.[9]

Research[edit]

Roelofs is an expert in affective neuroscience and stress-related disorders. She has provided the empirical foundations of current theorizing about the role of human defensive stress-reactions in long-term resilience[10]. Her group's longitudinal studies in risk populations[4] has contributed to the identification of biomarkers for stress-resilience[1]. Additionally, she is developing neurocognitively grounded interventions to train stress-resilience and decision making under threat[11][12], of which one is currently implemented in the curriculum of the Dutch Police Academy.[1] Roelofs’ theoretical paradigm opened new scientific directions, moving from a focus on stress vulnerability towards a focus on understanding resilience. She was awarded the prestigious international Evens Science Prize for outstanding neuroscientific contributions to the field of stress-resilience[1].

Awards and recognition[edit]

Roelofs holds various international positions[13]. She founding member and chair (2022-2024) of the International Resilience Alliance (INTRESA)[14] organizing symposia and publishing recommendations to advance the field. As founding member and vice-president (2020-2026) of the (AERG)[15] she focuses on fundamental science in Europe and organizes EU-wide debates and science events. She is elected member of the Academia Europaea AE[16] and the Royal Netherlands Academy of Arts and Sciences (KNAW)[6] and elected board member of the European federation of Academies of Sciences and Humanities (ALLEA) dedicated to the advancement of science and scholarship in Europe and the world.

Karin Roelofs has received several grants throughout her career. A selection of personal and consortium grants:

  • 2023 Dutch Research Council NWO take-off grant. Primary applicant: DUST platform (Decision under threat training), a biofeedback-based VR game. [9][4]
  • 2021Dutch Research Council (NWO) open competition SHH. Role applicant together with Ivan Toni: Control mechanisms of social-emotional regulation (406.20.GO.020) [9][17]
  • 2020 Dutch Research Council NWO Crossover Grant. Role WP-leader: INTENSE: Innovative Neurotechnology for Society.[9][18]
  • 2013-2019 Dutch Research Council (NWO): Vici personal grant, for “The role of freeze-fight-flight tendencies in post traumatic stress” [9][19]
  • 2018 European Research Council ERC Consolidator Grant. Primary applicant: DARE2APPROACH: A Neurocognitive Approach to Alleviating Persistent Avoidance in Anxiety Disorders (772337)[9][20]
  • 2017-2024 Horizon2020 Personalized Medicine grant. Co-applicant (PI: Kalisch): DYNAMORE: Dynamic modelling of resilience (777084777084)[9][6][18]
  • 2013-2017 European Research Council (ERC): FP7-HEALTH-2013-INNOVATION (co-applicant) [9]
  • 2017-2023 Dutch Research Council (NWO): Brain and Cognition Grant[9]
  • 2012-2018 European Research Council (ERC-StG) starting grant: Neural control of human freeze-fight-flight [9][21]

Public engagement[edit]

Roelofs regularly gives public lectures, several of which are publically available: "The Resilient Human Being" [23] (in dutch: De veerkrachtige mens) as part of the Dies Natalis event at Radboud University; "What causes you to freeze, flee or fight when you feel threatened?"[24] ( in dutch: Wat zorgt ervoor dat je verstijft, vlucht of juist vecht als je je bedreigd voelt?) was recorded as part of public lecture series of the University of the Netherlands (in dutch: de universiteit van nederland); and "Grensverleggen is... logisch"[25] organized by the Ministry of Defense of the Netherlands (in dutch: Ministrie van Defense); and a lecture on Veerkracht as part of the Radboud Reflects lecture series[26].

Roelofs’ work has been featured in several television programs and documentaries: The Evens Foundation Price video[1][27], Radboud Brain Awareness Week[28], "Martijn is Angry!" ( in dutch: Veilig Verkeer Nederland: Martijn is Boos![29][30]). VPRO-Labyrint[31] and Katja’s body scan.

Her work has been covered in newspapers and magazines, including the annual magazine of the Dutch Research Council (NWO): Results of 2022,[32] NeurolabNL,[33] European Commission Horizon (online magazine),[34] NWO.[35]

She also engaged in educating teachers and primary school children in research skills,[36] including workshops, lectures and a book on science for primary schools.[37]

Additionally, Roelofs' expertise has been sought in media interviews, including discussions on funding for fundamental research[48], the effects of stress on young children, and emotion regulation in psychopaths[38]. Lastly, her lab's efforts have been featured in numerous articles and radio segments in the Netherlands and Belgium[39].

Representative publications[40][edit]

References[edit]

  1. ^ a b c d e Foundation, Evens. "The Evens Science Prize 2020". Evens Foundation. Retrieved 2024-05-30.
  2. ^ Roelofs, Karin; Dayan, Peter (2022). "Freezing revisited: coordinated autonomic and central optimization of threat coping". Nature Reviews Neuroscience. 23 (9): 568–580. doi:10.1038/s41583-022-00608-2. ISSN 1471-003X. PMID 35760906.
  3. ^ Roelofs, Karin; Bramson, Bob; Toni, Ivan (2023). "A neurocognitive theory of flexible emotion control: The role of the lateral frontal pole in emotion regulation". Annals of the New York Academy of Sciences. 1525 (1): 28–40. Bibcode:2023NYASA1525...28R. doi:10.1111/nyas.15003. ISSN 0077-8923. PMID 37170478.
  4. ^ a b c Kaldewaij, Reinoud; Koch, Saskia B. J.; Hashemi, Mahur M.; Zhang, Wei; Klumpers, Floris; Roelofs, Karin (2021). "Anterior prefrontal brain activity during emotion control predicts resilience to post-traumatic stress symptoms". Nature Human Behaviour. 5 (8): 1055–1064. doi:10.1038/s41562-021-01055-2. ISSN 2397-3374. PMC 7611547. PMID 33603200.
  5. ^ Bramson, Bob; Meijer, Sjoerd; van Nuland, Annelies; Toni, Ivan; Roelofs, Karin (2023-08-12). "Anxious individuals shift emotion control from lateral frontal pole to dorsolateral prefrontal cortex". Nature Communications. 14 (1): 4880. Bibcode:2023NatCo..14.4880B. doi:10.1038/s41467-023-40666-3. ISSN 2041-1723. PMC 10423291. PMID 37573436.
  6. ^ a b c "Karin Roelofs - KNAW - KNAW". knaw.nl (in Dutch). Retrieved 2024-05-30.
  7. ^ "Zorgverlener opzoeken | BIG-register". zoeken.bigregister.nl. Retrieved 2024-05-30.
  8. ^ "Home". Roelofs Epan (in Dutch). Retrieved 2024-03-13.
  9. ^ a b c d e f g h i j k "Academy of Europe: Roelofs Karin". www.ae-info.org. Retrieved 2024-03-13.
  10. ^ Niermann, Hannah C. M.; Tyborowska, Anna; Cillessen, Antonius H. N.; van Donkelaar, Marjolein M.; Lammertink, Femke; Gunnar, Megan R.; Franke, Barbara; Figner, Bernd; Roelofs, Karin (2019). "The relation between infant freezing and the development of internalizing symptoms in adolescence: A prospective longitudinal study". Developmental Science. 22 (3): e12763. doi:10.1111/desc.12763. hdl:21.11116/0000-0003-5639-D. ISSN 1363-755X. PMID 30318656.
  11. ^ Hutschemaekers, Moniek H. M.; de Kleine, Rianne A.; Hendriks, Gert-Jan; Kampman, Mirjam; Roelofs, Karin (2021-08-20). "The enhancing effects of testosterone in exposure treatment for social anxiety disorder: a randomized proof-of-concept trial". Translational Psychiatry. 11 (1): 432. doi:10.1038/s41398-021-01556-8. ISSN 2158-3188. PMC 8379251. PMID 34417443.
  12. ^ NWO - Game Controlling stress through virtual reality https://www.nwo.nl/en/cases/game-controlling-stress-through-virtual-reality
  13. ^ Conclave - Europe 2040 Report (p70). https://europanova.eu/wp-content/uploads/2024/03/Conclave-Report-2023-2.pdf
  14. ^ "Members of INTRESA". intresa. 2015-11-04. Retrieved 2024-03-13.
  15. ^ Grantees, Association of ERC. "Governance • Association of ERC Grantees". Association of ERC Grantees. Retrieved 2024-03-13.
  16. ^ "Academy of Europe: List of Members". www.ae-info.org. Retrieved 2024-03-13.
  17. ^ "34 new projects start in Open Competition SSH | NWO". www.nwo.nl. 2021-05-04. Retrieved 2024-03-30.
  18. ^ a b https://www.politico.eu/wp-content/uploads/2024/03/19/rapportlight.pdf
  19. ^ "POLICE IN-ACTION: The role of freeze-fight-flight in posttraumatic stress symptoms | NWO". www.nwo.nl. 2014-02-01. Retrieved 2024-03-30.
  20. ^ "Dare to Approach: A Neurocognitive Approach to Alleviating Persistent Avoidance in Anxiety Disorders | DARE2APPROACH Project | Fact Sheet | H2020". CORDIS | European Commission. Retrieved 2024-03-30.
  21. ^ ERC 2012https://erc.europa.eu/sites/default/files/document/file/erc_2012_stg_results_sh.pdf
  22. ^ "Vidi 2007 | NWO". www.nwo.nl (in Dutch). 2001-11-21. Retrieved 2024-03-13.
  23. ^ Karin Roelofs, diesrede Dies Natalis Radboud Universiteit 2019. Retrieved 2024-03-30 – via www.youtube.com.
  24. ^ (2/5) Wat zorgt ervoor dat je verstijft, vlucht of juist vecht als je je bedreigd voelt?. Retrieved 2024-03-30 – via www.youtube.com.
  25. ^ Grensverleggen | Stress en freeze-fight-flight reacties - Karin Roelofs. Retrieved 2024-03-30 – via www.youtube.com.
  26. ^ Allemaal veerkrachtig | psycholoog Karin Roelofs en theoloog Michael Scherer-Rath. Retrieved 2024-03-30 – via www.youtube.com.
  27. ^ Evens Foundation (2022-09-27). Training the brain to cope with stress: Professor Karin Roelofs, Evens Science Prize 2020 laureate. Retrieved 2024-05-30 – via YouTube.
  28. ^ Faculty of Social Sciences (2022-03-14). Brain Awareness Week: reacties op traumatische ervaringen voorspellen en trainen. Retrieved 2024-05-30 – via YouTube.
  29. ^ "Martijn is boos! | Veilig Verkeer Nederland". vvn.nl (in Dutch). Retrieved 2024-03-30.
  30. ^ ""We hebben altijd een keuze hoe te reageren" | Veilig Verkeer Nederland". vvn.nl (in Dutch). 2019-11-15. Retrieved 2024-03-30.
  31. ^ Labyrint afl. 11: freeze-reactie bij trauma. Retrieved 2024-03-30 – via www.youtube.com.
  32. ^ "Game on! Controlling stress through virtual reality | NWO". www.nwo.nl. 2023-01-18. Retrieved 2024-03-30.
  33. ^ NeuroLabNL (2020-04-22). "Meet the Taskforce: Karin Roelofs". NeuroLabNL. Retrieved 2024-03-30.
  34. ^ "How do we make snap decisions? | Research and Innovation". projects.research-and-innovation.ec.europa.eu. 2018-09-11. Retrieved 2024-03-30.
  35. ^ "'I also exhibit freezing behaviour' | NWO". www.nwo.nl. 2017-10-17. Retrieved 2024-03-30.
  36. ^ Lezing 3 Stress en stressreacties. Retrieved 2024-03-30 – via www.youtube.com.
  37. ^ Wetenschappelijke doorbraken de klas in! https://www.wetenschapdeklasin.nl/uploads/boeken/Boek%206/Hoofdstuk%204/Boek%206%20H4%20Stress.pdf
  38. ^ Vermeulen, Margreet (21 June 2017). "Psychopaat voelt wel degelijk emoties; 'emotie-armoe is niet de kern van de aandoening'". de Volkskrant (in Dutch). Retrieved 2024-03-13.
  39. ^ "In the media". Roelofs Epan (in Dutch). Retrieved 2024-03-13.
  40. ^ "Prof. K. Roelofs (Karin) | Radboud University". www.ru.nl. Retrieved 2024-03-13.
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