GMCL1

GMCL1
Identifiers
Aliases	GMCL1, BTBD13, GCL, GCL1, SPATA29, germ cell-less, spermatogenesis associated 1, germ cell-less 1, spermatogenesis associated
External IDs	MGI: 1345156; HomoloGene: 8021; GeneCards: GMCL1; OMA:GMCL1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	69,881,384 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	86,710,365 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; gonad; ; testicle; ; Achilles tendon; ; rectum; ; monocyte; ; islet of Langerhans; ; duodenum; ; Epithelium of choroid plexus; ; jejunal mucosa;
	Top expressed in
	spermatocyte; ; superior cervical ganglion; ; seminiferous tubule; ; cumulus cell; ; molar; ; trigeminal ganglion; ; medullary collecting duct; ; hair follicle; ; primary oocyte; ; secondary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; identical protein binding;
Cellular component	nuclear matrix; nuclear envelope; ubiquitin ligase complex; nucleus;
Biological process	multicellular organism development; cell differentiation; regulation of transcription, DNA-templated; spermatogenesis;
	Sources:Amigo / QuickGO
Orthologs
	64395
	23885
	ENSG00000087338
	ENSMUSG00000001157
	Q96IK5
	Q920G9
	NM_178439
	NM_011818
	NP_848526
	NP_035948
	Wikidata
View/Edit Human	View/Edit Mouse

Germ cell-less, spermatogenesis associated 1 is a protein that in humans is encoded by the GMCL1 gene. ^[5]

Function

This gene encodes a nuclear envelope protein that appears to be involved in spermatogenesis, either directly or by influencing genes that play a more direct role in the process. This multi-exon locus is the homolog of the mouse and drosophila germ cell-less gene but the human genome also contains a single-exon locus on chromosome 5 that contains an open reading frame capable of encoding a highly related protein.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000087338 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001157 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Germ cell-less, spermatogenesis associated 1". Retrieved 2015-09-17.

Function

References

Further reading