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Hal Blumenfeld

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Hal Blumenfeld
Born (1962-03-28) March 28, 1962 (age 62)
California
EducationHarvard University Columbia University
Occupation(s)Professor of Neurology, Neuroscience, and Neurosurgery
Years active25
Known forConsciousness Research in Epilepsy
Medical career
FieldNeuroscience, Neurology
InstitutionsYale University School of Medicine

Massachusetts General Hospital/Harvard Medical School

Columbia Presbyterian Medical Center
AwardsResearch Recognition Award, Clinical Science, American Epilepsy Society (2017)

Javits Neuroscience Investigator Award, National Institute of Neurological Disorders and Stroke (2017)

Mark Loughridge and Michele Williams Professorship, Yale University School of Medicine (2015 - )

Yale Graduate Mentor Award (2015).

Visiting Professor, Xiangya School of Medicine, Changsha, Hunan, China (2015-2020).

Hal Blumenfeld (born March 28, 1962) is a professor of neurology, neuroscience, and neurosurgery[1] at Yale University. His focus is on brain mechanisms of consciousness and on altered consciousness in epilepsy.[2] As director of the Yale Clinical Neuroscience Imaging Center,[3] he leads multi-disciplinary research[4] and is also well known for his teaching contributions in neuroanatomy and clinical neuroscience.[5]

Biography

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Blumenfeld was born in California, grew up in New York and began his career in Bio-electrical Engineering at Harvard University (1984).[6] His passion for science would lead him to Columbia University where, working with Eric Kandel and Steven Siegelbaum, he obtained his PhD (1990) in Physiology and Cellular Biophysics and his MD (1992).[6][7][8] He completed his internal medicine internship at Columbia Presbyterian Medical Center(1993) and entered the field of neurology, completing a three-year residency program at Massachusetts General Hospital in Boston (1996). He then completed his fellowship at Yale University's School of Medicine.[9]

Career

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Blumenfeld has studied brain networks in different kinds of seizures as well as normal brain function. Using multiple modalities of brain imaging in humans and animal models, his research has made contributions towards determining why children with absence seizures become unconscious.[10][11][12][13][14]

Through active collaborations with Fahmeed Hyder[15] (also at Yale) Blumenfeld's direct recordings of the electrical activity of brain cells improves the analysis of indirect neuroimaging measurements of brain functions by fMRI.

Blumenfeld is the author of the textbook Neuroanatomy through Clinical Cases. The textbook is used in over half the medical schools in the United States and throughout the world.[16][17][18][19][20]

Awards

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Publications

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Books

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  • Blumenfeld, H. (2021). Neuroanatomy through Clinical Cases, 3rd Ed. Sinauer Associates/Oxford University Press.
  • Cavanna, A.E., Nani, A., Blumenfeld, H., Laureys, S. [Eds.] (2013). Neuroimaging of Consciousness. Springer.
  • Faingold, C., Blumenfeld, H. [Eds.] (2014). Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics. Elsevier ISBN 9780124158641.

Articles

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  • X Herman W, Smith RE, Kronemer SI, Watsky RE, Chen WC, M Gober L, Touloumes GJ, Khosla M, Raja A, Horien CL, C Morse E, L Botta K, Hirsch LJ, Alkawadri R, Gerrard JL, Spencer DD, Blumenfeld H:A Switch and Wave of Neuronal Activity in the Cerebral Cortex During the First Second of Conscious Perception. Cereb Cortex. 2017 Nov. PMID 29194517
  • Guo JN, Kim R, Chen Y, Negishi M, Jhun S, Weiss S, Ryu JH, Bai X, Xiao W, Feeney E, Rodriguez-Fernandez J, Mistry H, Crunelli V, Crowley MJ, Mayes LC, Constable RT, Blumenfeld H: Impaired consciousness in patients with absence seizures investigated by functional MRI, EEG, and behavioural measures: a cross-sectional study. Lancet Neurol. 2016 Dec. PMID 27839650
  • Kundishora AJ, Gummadavelli A, Ma C, Liu M, McCafferty C, Schiff ND, Willie JT, Gross RE, Gerrard J, Blumenfeld H: Restoring Conscious Arousal During Focal Limbic Seizures with Deep Brain Stimulation. Cereb Cortex. 2016 Mar 3; 2016 Mar 3. PMID 26941379
  • Zhan Q, Buchanan GF, Motelow JE, Andrews J, Vitkovskiy P, Chen WC, Serout F, Gummadavelli A, Kundishora A, Furman M, Li W, Bo X, Richerson GB, Blumenfeld H: Impaired Serotonergic Brainstem Function during and after Seizures. J Neurosci. 2016 Mar 2. PMID 26937010
  • Motelow JE, Li W, Zhan Q, Mishra AM, Sachdev RN, Liu G, Gummadavelli A, Zayyad Z, Lee HS, Chu V, Andrews JP, Englot DJ, Herman P, Sanganahalli BG, Hyder F, Blumenfeld H: Decreased subcortical cholinergic arousal in focal seizures. Neuron. 2015 Feb 4. PMID 25654258
  • Bailey CJ, Sanganahalli BG, Herman P, Blumenfeld H, Gjedde A, Hyder F: Analysis of time and space invariance of BOLD responses in the rat visual system. Cereb Cortex. 2013 Jan; 2012 Jan 31. PMID 22298731
  • Blumenfeld H. (2012). Impaired consciousness in epilepsy. The Lancet Neurology, 11: 814–826.
  • Mishra AM, Ellens DJ, Schridde U, Motelow JE, Purcaro MJ, DeSalvo MN, Enev M, Sanganahalli BG, Hyder F, Blumenfeld H: Where fMRI and electrophysiology agree to disagree: corticothalamic and striatal activity patterns in the WAG/Rij rat. J Neurosci. 2011 Oct 19. PMID 22016539
  • Englot DJ, Yang L, Hamid H, Danielson N, Bai X, Marfeo A, Yu L, Gordon A, Purcaro MJ, Motelow JE, Agarwal R, Ellens DJ, Golomb JD, Shamy MC, Zhang H, Carlson C, Doyle W, Devinsky O, Vives K, Spencer DD, Spencer SS, Schevon C, Zaveri HP, Blumenfeld H: Impaired consciousness in temporal lobe seizures: role of cortical slow activity. Brain. 2010 Dec; 2010 Nov 16. PMID 21081551
  • Bai X, Vestal M, Berman R, Negishi M, Spann M, Vega C, Desalvo M, Novotny EJ, Constable RT, Blumenfeld H: Dynamic time course of typical childhood absence seizures: EEG, behavior, and functional magnetic resonance imaging. J Neurosci. 2010 Apr 28. PMID 20427649
  • Englot DJ, Modi B, Mishra AM, DeSalvo M, Hyder F, Blumenfeld H: Cortical deactivation induced by subcortical network dysfunction in limbic seizures. J Neurosci. 2009 Oct 14. PMID 19828814
  • Blumenfeld H, Varghese GI, Purcaro MJ, Motelow JE, Enev M, McNally KA, Levin AR, Hirsch LJ, Tikofsky R, Zubal IG, Paige AL, Spencer SS: Cortical and subcortical networks in human secondarily generalized tonic-clonic seizures. Brain. 2009 Apr; 2009 Apr 1. PMID 19339252
  • Schridde U, Khubchandani M, Motelow JE, Sanganahalli BG, Hyder F, Blumenfeld H: Negative BOLD with large increases in neuronal activity. Cereb Cortex. 2008 Aug; 2007 Dec 5. PMID 18063563
  • Blumenfeld H, Klein JP, Schridde U, Vestal M, Rice T, Khera DS, Bashyal C, Giblin K, Paul-Laughinghouse C, Wang F, Phadke A, Mission J, Agarwal RK, Englot DJ, Motelow J, Nersesyan H, Waxman SG, Levin AR: Early treatment suppresses the development of spike-wave epilepsy in a rat model. Epilepsia. 2008 Mar; 2007 Dec 6. PMID 18070091
  • Blumenfeld H, McNally KA, Vanderhill SD, Paige AL, Chung R, Davis K, Norden AD, Stokking R, Studholme C, Novotny EJ Jr, Zubal IG, Spencer SS: Positive and negative network correlations in temporal lobe epilepsy. Cereb Cortex. 2004 Aug; 2004 Apr 14. PMID 15084494

References

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  1. ^ http://medfaculty.yale.edu/programs/hal_blumenfeld.profile[permanent dead link]
  2. ^ "Connecticut's Best Doctors 2018". connecticutmag.com.
  3. ^ "CNIC Labs > Clinical Neurosciences Imaging Center (CNIC) - Neurology - Yale School of Medicine". cnic.yale.edu.
  4. ^ "Home > Blumenfeld Lab - Neurology - Yale School of Medicine". medicine.yale.edu.
  5. ^ "Graduate Mentor Awards | Yale Graduate School of Arts & Sciences". Gsas.yale.edu. 2015-05-21. Retrieved 2017-05-03.
  6. ^ a b Curriculum Vitae. Blumenfeld, H. (Accessed 20 May 2021). https://prod.admin.profile.yale.edu/Profiles/Cv/user/hal_blumenfeld
  7. ^ "Alumni Directory". columbia.edu. 13 April 2015.
  8. ^ Blumenfeld, Hal (1990). Modulation of intracellular calcium in Aplysia sensory neurons (Thesis).
  9. ^ "Profile". Yale School of Medicine - Official website. Retrieved 30 September 2021.
  10. ^ Guo, Jennifer N.; Kim, Robert; Chen, Yu; Negishi, Michiro; Jhun, Stephen; Weiss, Sarah; Ryu, Jun Hwan; Bai, Xiaoxiao; Xiao, Wendy; Feeney, Erin; Rodriguez-Fernandez, Jorge (December 2016). "Impaired consciousness in patients with absence seizures investigated by functional MRI, EEG, and behavioural measures: a cross-sectional study". The Lancet. Neurology. 15 (13): 1336–1345. doi:10.1016/S1474-4422(16)30295-2. ISSN 1474-4465. PMC 5504428. PMID 27839650.
  11. ^ Blumenfeld, Hal (2005). "Consciousness and epilepsy: why are patients with absence seizures absent?". The Boundaries of Consciousness: Neurobiology and Neuropathology. Progress in Brain Research. Vol. 150. pp. 271–286. doi:10.1016/S0079-6123(05)50020-7. ISBN 9780444518514. ISSN 0079-6123. PMC 3153469. PMID 16186030.
  12. ^ Bai, Xiaoxiao; Vestal, Matthew; Berman, Rachel; Negishi, Michiro; Spann, Marisa; Vega, Clemente; Desalvo, Matthew; Novotny, Edward J.; Constable, Robert T.; Blumenfeld, Hal (2010-04-28). "Dynamic time course of typical childhood absence seizures: EEG, behavior, and functional magnetic resonance imaging". The Journal of Neuroscience. 30 (17): 5884–5893. doi:10.1523/JNEUROSCI.5101-09.2010. ISSN 1529-2401. PMC 2946206. PMID 20427649.
  13. ^ Bai, X.; Guo, J.; Killory, B.; Vestal, M.; Berman, R.; Negishi, M.; Danielson, N.; Novotny, E. J.; Constable, R. T.; Blumenfeld, H. (2011-06-07). "Resting functional connectivity between the hemispheres in childhood absence epilepsy". Neurology. 76 (23): 1960–1967. doi:10.1212/WNL.0b013e31821e54de. ISSN 1526-632X. PMC 3109878. PMID 21646622.
  14. ^ Killory, Brendan D.; Bai, Xiaoxiao; Negishi, Michiro; Vega, Clemente; Spann, Marisa N.; Vestal, Matthew; Guo, Jennifer; Berman, Rachel; Danielson, Nathan; Trejo, Jerry; Shisler, David (2011-06-15). "Impaired attention and network connectivity in childhood absence epilepsy". NeuroImage. 56 (4): 2209–2217. doi:10.1016/j.neuroimage.2011.03.036. ISSN 1095-9572. PMC 3105167. PMID 21421063.
  15. ^ http://medfaculty.yale.edu/about/fahmeed_hyder.profile?source=news [dead link]
  16. ^ "Ultimate guide to buying your Neuroscience Textbooks". The Brainworm. Retrieved 2017-05-03.
  17. ^ Hal Blumenfeld (2010-02-28). Neuroanatomy Through Clinical Cases (2nd ed.). Booktopia. ISBN 9780878936137. Retrieved 2017-05-03.
  18. ^ "SYLLABUS: MEDICAL NEUROSCIENCE" (PDF). Tulane.edu. Retrieved 2017-05-03.
  19. ^ "Required and recommended textbook list" (PDF). Medicine.tufts.edu. Retrieved 2017-05-03.
  20. ^ "Book Review: Neuroanatomy through Clinical Cases". The Neuroradiology Journal. 26 (3): 358–360. June 2013. doi:10.1177/197140091302600319. ISSN 1971-4009. PMC 5278855.
  21. ^ "Blumenfeld receives prestigious award that supports research into seizures - Yale School of Medicine". yale.edu.
  22. ^ "2017 Awardees | American Epilepsy Society". Archived from the original on 2018-04-12. Retrieved 2018-04-11.
  23. ^ "Graduate Mentor Awards - Yale Graduate School of Arts & Sciences". gsas.yale.edu.
  24. ^ "From the inner city to Yale and neurosurgery > Students > Autumn 2007 - Yale Medicine". ymm.yale.edu.
  25. ^ "Awards History". www.aan.com.
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