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Henry J. M. Barnett

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Henry Joseph Macaulay Barnett
Born(1922-02-10)February 10, 1922
DiedOctober 20, 2016(2016-10-20) (aged 94)
Alma materUniversity of Toronto
Occupation(s)Physician, researcher
Known forPresident of Robarts Research Institute
AwardsOrder of Canada, honorary Doctor of Laws degree, honorary Doctor or Science degree

Henry Joseph Macaulay Barnett CC (February 10, 1922 – October 20, 2016) was a Canadian physician and neurologist, a leading stroke researcher as a result of being the principal investigator in several major clinical trials. As a clinical scientist, he did pioneering research in stroke prevention, beginning with the use of aspirin.[1]

Born in Newcastle upon Tyne, England, he graduated from the University of Toronto Schools and received his medical degree from the University of Toronto in 1944.[2]

He started to work at the University Hospital in London, Ontario and the University of Western Ontario in 1974, published the results of his clinical trials in the New England Journal of Medicine.[3][4][5] In 1978, he published the results of his clinical trial demonstrating the effectiveness of aspirin in preventing stroke.[3] In 1985, he showed the ineffectiveness of then commonly performed bypass surgery re-routing blood flow from the extracranial to the intracranial circulation,[4] thus saving patients from needless surgery by showing ineffectiveness of the surgical procedure in stroke prevention. He found effectiveness, however, in preventing stroke by another common surgical procedure, carotid endarterectomy, which removes atherosclerotic plaque from the bifurcation of the carotid artery in the neck.[5]

From its founding in 1986, he was the president and scientific director of Robarts Research Institute until his retirement in 1995.

In 1984 he was made an Officer of the Order of Canada and was promoted to Companion in 2003. In 1995 he was inducted into the Canadian Medical Hall of Fame. In 2001 he was awarded an honorary Doctor of Laws degree from the University of Western Ontario, and in 2012 he was awarded an honorary Doctor of Science degree from the University of Oxford.

The Heart and Stroke Foundation of Canada's Henry JM Barnett Research Scholarship Award is named in his honour. He died in Toronto on October 20, 2016.[6]

References[edit]

  1. ^ "Obituary of Henry Barnett". humphreymiles.com. Retrieved 27 October 2016.
  2. ^ Diane Peters, "Neurologist Henry Barnett proved Aspirin prevents strokes," Globe and Mail, Nov. 23, 2016.
  3. ^ a b Barnett, HJM (1978). "A randomized trial of aspirin and sulfinpyrazone in threatened stroke". New England Journal of Medicine. 299 (2): 53-59. doi:10.1056/NEJM197807132990201. PMID 351394.
  4. ^ a b Barnett, HJM; The EC/IC bypass study group (1985). "Failure of extracranial-inracranial arterial bypass to reduce the risk of ischemic stroke. Results of an international randomized trial". New England Journal of Medicine. 313 (19): 1191-1200. doi:10.1056/NEJM198511073131904. PMID 2865674.
  5. ^ a b Barnett, HJM; Taylor, DW; Haynes, RB; Sackett, DL; Peerless, SJ; Ferguson, GG; Fox, AJ; Rankin, RN; Hachinski, VC; Wiebers, DO; Eliasziw, M (1991). "Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis". New England Journal of Medicine. 325 (7): 445-453. doi:10.1056/NEJM199108153250701. PMID 1852179.
  6. ^ "Obituary of Henry Joseph Barnett | Humphrey Funeral Home A.W. Miles-Newbigging Chapel Limited".