Jump to content

英文维基 | 中文维基 | 日文维基 | 草榴社区

João Pedro de Magalhães

From Wikipedia, the free encyclopedia
João Pedro de Magalhães
Born
NationalityPortuguese
Alma materCatólica
Scientific career
InstitutionsUniversity of Birmingham

Joao Pedro De Magalhaes is a Portuguese molecular biologist. He studies aging through both computational and experimental approaches.

In 1999, he obtained his degree in Microbiology from Escola Superior de Biotecnologia. Under Olivier Toussaint, he obtained his PhD from the University of Namur in 2004. Then he did a postdoc in the George Church lab at Harvard Medical School from 2004 to 2008.[1]

In 2008, he was recruited by the University of Liverpool to lead a lab studying genomic approaches to aging. In 2022, he was recruited by the University of Birmingham to be Chair of Molecular Biogerontology, and he currently leads the Genomics of Aging and Rejuvenation Lab there.[2]

He helps maintain several databases on aging - among them - GenAge, AnAge, DrugAge,[3] CellAge, GenDR, the Digital Aging Atlas,[4] and Who's Who in Gerontology. His research group helped sequence the transcriptome of the long-lived bowhead whale. He also helps advise the Lifeboat Foundation.

Among his many longevity-related scientific research projects, Magalhães has sequenced and analyzed the genome of the bowhead whale.[5] And he has also contributed to analysis of the genome of the naked mole rat.[6] Both of these mammals are exceptionally long-lived and exceptionally cancer-resistant.

References

[edit]
  1. ^ "Lifeboat Foundation". Archived from the original on 2015-04-13. Retrieved 2015-05-05.
  2. ^ "Professor Joao Pedro Magalhaes PhD". Archived from the original on 2022-10-24. Retrieved 2022-10-24.
  3. ^ Barardo D, Thornton D, Thoppil H, Walsh M, Sharifi S, Ferreira S, Anžič A, Fernandes M, Monteiro P, Grum T, Cordeiro R, De-Souza EA, Budovsky A, Araujo N, Gruber J, Petrascheck M, Fraifeld VE, Zhavoronkov A, Moskalev A, de Magalhães JP (2017). "The DrugAge database of aging-related drugs". Aging Cell. 16 (3): 594–597. doi:10.1111/acel.12585. PMC 5418190. PMID 28299908.
  4. ^ "Welcome to the Digital Ageing Atlas, the portal of ageing related changes". Ageing-map.org. Retrieved May 29, 2015.
  5. ^ Keane M, Semeiks J, Webb AE, Li YI, Quesada V, Craig T, Madsen LB, van Dam S, Brawand D, Marques PI, Michalak P, Kang L, Bhak J, Yim HS, Grishin NV, Nielsen NH, Heide-Jørgensen MP, Oziolor EM, Matson CW, Church GM, Stuart GW, Patton JC, George JC, Suydam R, Larsen K, López-Otín C, O'Connell M, Bickham JW, Thomsen B, de Magalhães JP (2015). "Insights into the evolution of longevity from the bowhead whale genome". Cell Reports. 10 (1): 112–122. doi:10.1016/j.celrep.2014.12.008. PMC 4536333. PMID 25565328.
  6. ^ Keane M, Craig T, Alföldi J, Berlin AM, Johnson J, Seluanov A, Gorbunova V, Di Palma F, Lindblad-Toh K, Church GM, de Magalhães JP (2014). "The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations". Bioinformatics. 30 (24): 3558–3560. doi:10.1093/bioinformatics/btu579. PMC 4253829. PMID 25172923.
[edit]