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R-16661

From Wikipedia, the free encyclopedia
R-16661
Names
IUPAC name
2-(Methoxy(methylthio)phosphinylimino)-3-ethyl-5-methyl-1,3-oxazolidine
Other names
Stauffer R-16661
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C8H17N2O3PS/c1-5-10-6-7(2)13-8(10)9-14(11,12-3)15-4/h7H,5-6H2,1-4H3/b9-8+
    Key: JCYANUVOCLKHHY-CMDGGOBGSA-N
  • CCN1CC(OC1=NP(=O)(OC)SC)C
Properties
C8H17N2O3PS
Molar mass 252.27 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Extremely toxic
Lethal dose or concentration (LD, LC):
0.1 mg/kg (mice, oral)
0.1 mg/kg (rats, oral)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

R-16661 is an extremely toxic organophosphate insecticide. With an oral LD50 of 0.1 mg/kg in mice and rats, R-16661 is about 10 times more toxic than aldicarb, the most toxic carbamate insecticide.[1][2]

See also

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References

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  1. ^ Fukuto, T.R.; Shrivastava, S.P.; Black, A.L. (June 1972). "Metabolism of 2-[methoxy(methylthio)phosphinylimino]-3-ethyl-5-methyl-1,3-oxazolidine in the cotton plant and houseflies". Pesticide Biochemistry and Physiology. 2 (2): 162–169. doi:10.1016/0048-3575(72)90019-3.
  2. ^ "Pesticidal phosphorous-containing imino oxazolidines".