RTI-160
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| Formula | C18H24N2O3 |
| Molar mass | 316.401 g·mol−1 |
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RTI-160 (benzoylecgonine dimethylamide) is a tropane derivative drug with stimulant effects, having similar potency as a dopamine reuptake inhibitor to cocaine. It is synthesized by an amide condensation reaction between benzoylecgonine and dimethylamine.[1][2]
See also
[edit]- 3-(p-Fluorobenzoyloxy)tropane
- 4′-Fluorococaine
- Cocaethylene
- Cocaine reverse ester
- RTI-229
- Salicylmethylecgonine
References
[edit]- ^ Carroll FI, Kotian P, Dehghani A, Gray JL, Kuzemko MA, Parham KA, et al. (January 1995). "Cocaine and 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter". Journal of Medicinal Chemistry. 38 (2): 379–388. doi:10.1021/jm00002a020. PMID 7830281.
- ^ Paula S, Tabet MR, Farr CD, Norman AB, Ball WJ (January 2004). "Three-dimensional quantitative structure-activity relationship modeling of cocaine binding by a novel human monoclonal antibody". Journal of Medicinal Chemistry. 47 (1): 133–142. doi:10.1021/jm030351z. PMID 14695827.