Jump to content

英文维基 | 中文维基 | 日文维基 | 草榴社区

TP53INP1

From Wikipedia, the free encyclopedia
TP53INP1
Identifiers
AliasesTP53INP1, SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1, tumor protein p53 inducible nuclear protein 1
External IDsOMIM: 606185; MGI: 1926609; HomoloGene: 11065; GeneCards: TP53INP1; OMA:TP53INP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001135733
NM_033285

NM_001199105
NM_021897

RefSeq (protein)

NP_001129205
NP_150601

NP_001186034
NP_068697

Location (UCSC)Chr 8: 94.93 – 94.95 MbChr 4: 11.16 – 11.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tumor protein p53-inducible nuclear protein 1 is a protein that in humans is encoded by the TP53INP1 gene.[5][6][7] In mice this protein is also called TRP53INP1 and is encoded by the Trp53inp1 gene. The protein is also referred to as SIP or "stress inducible protein"


Interactions

[edit]

TP53INP1 has been shown to interact with HIPK2[8] and p53.[5][8]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164938Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028211Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Okamura S, Arakawa H, Tanaka T, Nakanishi H, Ng CC, Taya Y, Monden M, Nakamura Y (Aug 2001). "p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis". Mol Cell. 8 (1): 85–94. doi:10.1016/S1097-2765(01)00284-2. PMID 11511362.
  6. ^ Nowak J, Tomasini R, Mattei MG, Azizi Samir LA, Dagorn JC, Dusetti N, Iovanna JL, Pebusque MJ (Nov 2002). "Assignment of tumor protein p53 induced nuclear protein 1 (TP53INP1) gene to human chromosome band 8q22 by in situ hybridization". Cytogenet Genome Res. 97 (1–2): 140E. doi:10.1159/000064049. PMID 12438758.
  7. ^ "Entrez Gene: TP53INP1 tumor protein p53 inducible nuclear protein 1".
  8. ^ a b Tomasini, Richard; Samir Amina Azizi; Carrier Alice; Isnardon Daniel; Cecchinelli Barbara; Soddu Silvia; Malissen Bernard; Dagorn Jean-Charles; Iovanna Juan L; Dusetti Nelson J (Sep 2003). "TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity". J. Biol. Chem. 278 (39). United States: 37722–9. doi:10.1074/jbc.M301979200. ISSN 0021-9258. PMID 12851404.

Further reading

[edit]