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User:Mr. Ibrahem/Insulin glulisine

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Mr. Ibrahem/Insulin glulisine
PDB: 6gv0
Clinical data
Trade namesApidra, Apidra SoloStar
AHFS/Drugs.comMonograph
MedlinePlusa607033
License data
Pregnancy
category
Routes of
administration
Subcutaneous, intravenous
Drug classInsulin (rapid acting)[2]
Legal status
Legal status
Chemical and physical data
FormulaC258H384N64O78S6
Molar mass5822.64 g·mol−1
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Insulin glulisine, sold under the brand name Apidra, is a rapid acting insulin used to treat type 1 and type 2 diabetes.[2] It is given by injection under the skin between 15 minutes before to 20 minutes after starting a meal.[2] It may also be used by injection into a vein.[3] It is generally used with a long acting insulin.[2]

Common side effects include low blood sugar and pain at the site of injection.[4][2] Other side effects may include allergic reactions, low potassium, and lipodystrophy.[2] It is made by recombinant DNA techniques.[4]

Insulin glulisine was approved for medical use in the United States and Europe in 2004.[2][4] In the United Kingdom 300 units costs the NHS about £6 as of 2021.[5] In the United States this amount costs just over 100 USD.[6]

References[edit]

  1. ^ a b "Insulin glulisine Use During Pregnancy". Drugs.com. 6 April 2020. Archived from the original on 4 December 2020. Retrieved 21 September 2020.
  2. ^ a b c d e f g h i "Insulin Glulisine Monograph for Professionals". Drugs.com. Archived from the original on 8 August 2020. Retrieved 26 November 2021.
  3. ^ a b "Apidra- insulin glulisine injection, solution Apidra SoloStar- insulin glulisine injection, solution". DailyMed. 6 December 2019. Archived from the original on 25 March 2021. Retrieved 21 September 2020.
  4. ^ a b c d e "Apidra EPAR". European Medicines Agency (EMA). Archived from the original on 10 October 2020. Retrieved 7 October 2020.
  5. ^ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 754. ISBN 978-0857114105.
  6. ^ "Apidra Prices, Coupons & Savings Tips". GoodRx. Archived from the original on 11 December 2021. Retrieved 26 November 2021.