User:Mr. Ibrahem/Rimantadine
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| Clinical data | |
|---|---|
| Trade names | Flumadine |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a698029 |
| Pregnancy category |
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| Routes of administration | By mouth |
| Drug class | Adamantane[1] |
| Legal status | |
| Legal status |
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| Pharmacokinetic data | |
| Bioavailability | well absorbed |
| Protein binding | 40% |
| Metabolism | Liver hydroxylation and glucuronidation |
| Elimination half-life | 25.4 ± 6.3 hours |
| Excretion | Kidney |
| Identifiers | |
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| Chemical and physical data | |
| Formula | C12H21N |
| Molar mass | 179.307 g·mol−1 |
| 3D model (JSmol) | |
| Chirality | Racemic mixture |
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| (verify) | |
Rimantadine, sold under the brand name Flumadine, is an antiviral medication that was used to treat and prevent influenza A. [2] Due to the development of resistance such use is no longer generally recommended.[2] It is taken by mouth.[2]
Common side effects include nausea, trouble sleeping, and dizziness.[2] Other side effects may include seizures.[2] Safety in pregnancy is unclear.[3] It used to work by interfering with the M2 protein.[2]
Rimantadine was approved for medical use in the United States in 1993.[2] In the United States it costs about 23 USD for a week as of 2021.[4]
References[edit]
- ^ "Antiviral medicines for pandemic influenza". Archived from the original on 12 August 2021. Retrieved 17 October 2021.
- ^ a b c d e f g h i "RiMANTAdine Monograph for Professionals". Drugs.com. Archived from the original on 14 August 2021. Retrieved 17 October 2021.
- ^ "Rimantadine (Flumadine) Use During Pregnancy". Drugs.com. Archived from the original on 29 October 2020. Retrieved 17 October 2021.
- ^ "Rimantadine Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 17 October 2021.