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7-F-5-MeO-MET

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5-MeO-7-F-MET
Identifiers
  • N-ethyl-2-(7-fluoro-5-methoxy-1H-indol-3-yl)-N-methylethanamine
PubChem CID
Chemical and physical data
FormulaC14H19FN2O
Molar mass250.317 g·mol−1
3D model (JSmol)
  • CCN(C)CCC1=CNC2=C1C=C(C=C2F)OC
  • InChI=1S/C14H19FN2O/c1-4-17(2)6-5-10-9-16-14-12(10)7-11(18-3)8-13(14)15/h7-9,16H,4-6H2,1-3H3
  • Key:IKYKXFMGTKYLAU-UHFFFAOYSA-N

7-F-5-MeO-MET (5-MeO-7-F-MET, 5-Methoxy-7-fluoro-N-methyl-N-ethyltryptamine) is a tryptamine derivative which acts as a serotonin receptor agonist selective for the 5-HT2 subtypes, with a pEC50 of 8.71 at 5-HT2A, vs 8.25 at 5-HT2B and 7.69 at 5-HT2C. In animal tests it produced the most potent head-twitch response of a range of related fluorinated tryptamine derivatives tested, though still with slightly lower potency than psilocybin.[1]

See also

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References

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  1. ^ WO 2022/256554, Wallach J, Dybek M, "Fluorinated Tryptamine Compounds, Analogues Thereof, and Methods Using Same", published 8 December 2022, assigned to University of the Sciences in Philadelphia. 


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