Lithium citrate
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| Names | |
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| Other names
Trilithium citrate
trilithium 2-hydroxypropane-1,2,3-tricarboxylate | |
| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| DrugBank | |
| ECHA InfoCard | 100.011.860 |
| EC Number |
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PubChem CID
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| RTECS number |
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| Li3C6H5O7 | |
| Molar mass | 209.923 g mol−1 |
| Appearance | Odorless white powder |
| Melting point | decomposes at 105 °C (221 °F; 378 K) |
| Hazards | |
| GHS labelling: | |
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| Warning | |
| H302, H319 | |
| P305+P351+P338 | |
| Flash point | N/A |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Lithium citrate (Li3C6H5O7) is a lithium salt of citric acid that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder.[1][2][3][4] There is extensive pharmacology of lithium, the active component of this salt.
Lithia water contains various lithium salts, including the citrate.
History
[edit]An early version of Coca-Cola available in pharmacies' soda fountains called Lithia Coke was a mixture of Coca-Cola syrup and lithia water. The soft drink 7Up was originally named "Bib-Label Lithiated Lemon-Lime Soda" when it was formulated in 1929 because it contained lithium citrate. The beverage was a patent medicine marketed as a cure for hangover. Lithium citrate was removed from 7Up in 1948[5] after the Food and Drug Administration banned its use in soda.[6]
Lithium citrate is used as a mood stabilizer and is used to treat mania, hypomania, depression and bipolar disorder.[7] It can be administered orally in the form of a syrup.[7]
References
[edit]- ^ Medication description
- ^ "pms-Lithium Citrate - Uses, Side Effects, Interactions - MedBroadcast.com". medbroadcast.com. Retrieved 2017-08-15.
- ^ "Medical use". Archived from the original on 2006-06-15. Retrieved 2006-07-29.
- ^ "Lithium: medicine to control mood disorders such as mania and bipolar disorder". nhs.uk. 2020-08-17. Retrieved 2022-08-25.
- ^ Gielen, Marcel; Edward R. T. Tiekink (2005). Metallotherapeutic drugs and metal-based diagnostic agents: The use of metals in medicine. John Wiley and Sons. p. 3. ISBN 0-470-86403-6.
- ^ "Here's the Gross Thing That Happens when You Mix 7-Up with Lithium". 20 February 2016.
- ^ a b PubChem. "Lithium citrate". pubchem.ncbi.nlm.nih.gov. Retrieved 2022-09-08.
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